Metformin influences drug sensitivity in pancreatic cancer cells.

Candido S, Abrams SL, Steelman L, Lertpiriyapong K, Martelli AM, Cocco L, Ratti S, Follo MY, Murata RM, Rosalen PL, Lombardi P, Montalto G, Cervello M, Gizak A, Rakus D, Suh PG, Libra M, McCubrey JA

[Adv Biol Regul. 2018 Feb 12. pii: S2212-4926(18)30074-5]

Phospholipase Cγ1 links inflammation and tumorigenesis in colitis-associated cancer.

Park KI, Kim KY, Oh TW, Kang DS, Kim EK, Yang YR, Seo YK, Ma JY, Suh PG

[Oncotarget. 2017 Dec 19;9(5):5752-5763]

PLCγ1: Potential arbitrator of cancer progression.

Jang HJ, Suh PG, Lee YJ, Shin KJ, Cocco L, Chae YC

[Adv Biol Regul. 2018 Jan;67:1-6]

Nuclear inositide signaling and cell cycle.

Ratti S, Ramazzotti G, Faenza I, Fiume R, Mongiorgi S, Billi AM, McCubrey JA, Suh PG, Manzoli L, Cocco L, Follo MY

[Adv Biol Regul. 2018 Jan;67:1-6]

Dynamic relocalization of NHERF1 mediates chemotactic migration of ovarian cancer cells toward lysophosphatidic acid stimulation.

Oh YS, Heo K, Kim EK, Jang JH, Bae SS, Park JB, Kim YH, Song M, Kim SR, Ryu SH, Kim IH, Suh PG

[Exp Mol Med. 2017 Jul 7;49(7):e351]

Forebrain-specific ablation of phospholipase Cγ1 causes manic-like behavior.

Yang YR, Jung JH, Kim SJ, Hamada K, Suzuki A, Kim HJ, Lee JH, Kwon OB, Lee YK, Kim J, Kim EK, Jang HJ, Kang DS, Choi JS, Lee CJ, Marshall J, Koh HY, Kim CJ, Seok H, Kim SH, Choi JH, Choi YB, Cocco L, Ryu SH, Kim JH, Suh PG

[Mol Psychiatry. 2017 Oct;22(10):1473-1482]

Nudix-type motif 2 contributes to cancer proliferation through the regulation of Rag GTPase-mediated mammalian target of rapamycin complex 1 localization.

Kwon O, Kwak D, Ha SH, Jeon H, Park M, Chang Y, Suh PG, Ryu SH

[Cell Signal. 2017 Apr;32:24-35]

Accelerated Bone Regeneration by Two-Photon Photoactivated Carbon Nitride Nanosheets.

Tiwari JN, Seo YK, Yoon T, Lee WG, Cho WJ, Yousuf M, Harzandi AM, Kang DS, Kim KY, Suh PG, Kim KS

[ACS Nano. 2017 Jan 24;11(1):742-751]

The thalamic mGluR1-PLCβ4 pathway is critical in sleep architecture.

Hong J, Lee J, Song K, Ha GE, Yang YR, Ma JS, Yamamoto M, Shin HS, Suh PG, Cheong E

[Mol Brain. 2016 Dec 21;9(1):100]

SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy.

Kim KY, Jang HJ, Yang YR, Park KI, Seo J, Shin IW, Jeon TI, Ahn SC, Suh PG, Osborne TF, Seo YK

[Sci Rep. 2016 Oct 21;6:35732]

G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion.

Lee YJ, Shin KJ, Park SA, Park KS, Park S, Heo K, Seo YK, Noh DY, Ryu SH, Suh PG

[Oncotarget. 2016 Oct 25;7(43):70898-70911]

Phospholipid-related signaling in physiology and pathology.

Suh PG, Cocco L.

[Adv Biol Regul. 2016 May;61:1]

Molecular Mechanisms Underlying Psychological Stress and Cancer.

Shin KJ, Lee YJ, Yang YR, Park S, Suh PG, Follo MY, Cocco L, Ryu SH

[Curr Pharm Des. 2016;22(16):2389-402]

PPARγ Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose Tissue.

Choi SS, Kim ES, Jung JE, Marciano DP, Jo A, Koo JY, Choi SY, Yang YR, Jang HJ, Kim EK, Park J, Kwon HM, Lee IH, Park SB, Myung KJ, Suh PG, Griffin PR, Choi JH

[Diabetes. 2016 Apr;65(4):829-39]

Mouse Sphingosine Kinase 1a Is Negatively Regulated through Conventional PKC-Dependent Phosphorylation at S373 Residue.

Oh YS, Bae SS, Park JB, Ha SH, Ryu SH, Suh PG

[PLoS One. 2015 Dec 7;10(12):e0143695]

Primary phospholipase C and brain disorders.

Yang YR, Kang DS, Lee C, Seok H, Follo MY, Cocco L, Suh PG

[Adv Biol Regul. 2016 May;61:80-5]

Roles of phosphoinositide-specific phospholipase Cγ1 in brain development.

Kang DS, Yang YR, Lee C, Kim S, Ryu SH, Suh PG

[Adv Biol Regul. 2016 Jan;60:167-173]

Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivity.

Choi S, Jung JE, Yang YR, Kim ES, Jang HJ, Kim EK, Kim IS, Lee JY, Kim JK, Seo JK, Kim JM, Park J, Suh PG, Choi JH

[Cell Signal. 2015 Dec;27(12):2488-95]

Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga(+/-) mice.

Yang YR, Jang HJ, Choi SS, Lee YH, Lee GH, Seo YK, Choi JH, Park D, Koh A, Kim IS, Lee H, Ryu SH, Suh PG

[Diabetologia. 2015 Dec;58(12):2867-76]

GTP-dependent interaction between phospholipase D and dynamin modulates fibronectin-induced cell spreading.

Lee CS, Kim JM, Ghim J, Suh PG, Ryu SH

[Cell Signal. 2015 Dec;27(12):2363-70]

O-GlcNAc cycling enzymes control vascular development of the placenta by modulating the levels of HIF-1α.

Yang YR, Jang HJ, Lee YH, Kim IS, Lee H, Ryu SH, Suh PG

[Placenta. 2015 Oct;36(10):1063-8]

Analysis of Interactions between the Epidermal Growth Factor Receptor and Soluble Ligands on the Basis of Single-Molecule Diffusivity in the Membrane of Living Cells.

Kim DH, Zhou K, Kim DK, Park S, Noh J, Kwon Y, Kim D, Song NW, Lee JB, Suh PG, Lee NK, Ryu SH

[Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7028-32]

Identification of novel phosphatidic acid-binding proteins in the rat brain.

Park C, Kang DS, Shin GH, Seo J, Kim H, Suh PG, Bae CD, Shin JH

[Neurosci Lett. 2015 May 19;595:108-13]

Flightless-1, a novel transcriptional modulator of PPARγ through competing with RXRα.

Choi JS, Choi SS, Kim ES, Seo YK, Seo JK, Kim EK, Suh PG, Choi JH

[Cell Signal. 2015 Mar;27(3):614-20]

Thrap3 docks on phosphoserine 273 of PPARγ and controls diabetic gene programming.

Choi JH, Choi SS, Kim ES, Jedrychowski MP, Yang YR, Jang HJ, Suh PG, Banks AS, Gygi SP, Spiegelman BM

[Genes Dev. 2014 Nov 1;28(21):2361-9]

A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity.

Choi SS, Kim ES, Koh M, Lee SJ, Lim D, Yang YR, Jang HJ, Seo KA, Min SH, Lee IH, Park SB, Suh PG, Choi JH

[J Biol Chem. 2014 Sep 19;289(38):26618-29]

Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim.

Park HK, Lee JE, Lim J, Jo DE, Park SA, Suh PG, Kang BH

[BMC Cancer. 2014 Jun 13;14:431]

RhoA and Rac1 play independent roles in lysophosphatidic acid-induced ovarian cancer chemotaxis.

Hwang H, Kim EK, Park J, Suh PG, Cho YK

[Integr Biol (Camb). 2014 Mar;6(3):267-76]

O-GlcNAcylation in cellular functions and human diseases.

Yang YR, Suh PG

[Adv Biol Regul. 2014 Jan;54:68-73]

Periostin-binding DNA aptamer inhibits breast cancer growth and metastasis.

Lee YJ, Kim IS, Park SA, Kim Y, Lee JE, Noh DY, Kim KT, Ryu SH, Suh PG

[Mol Ther. 2013 May;21(5):1004-13]

DJ-1 promotes angiogenesis and osteogenesis by activating FGF receptor-1 signaling.

Kim JM, Shin HI, Cha SS, Lee CS, Hong BS, Lim S, Jang HJ, Kim J, Yang YR, Kim YH, Yun S, Rijal G, Lee-Kwon W, Seo JK, Gho YS, Ryu SH, Hur EM, Suh PG

[Nat Commun. 2012;3:1296]